CDS
| Accession Number | TCMCG040C24916 |
| gbkey | CDS |
| Protein Id | RDX89941.1 |
| Location | join(<30346..31245,31419..31583) |
| Gene | THI1-2 |
| Organism | Mucuna pruriens |
| locus_tag | CR513_28258 |
Protein
| Length | 354aa |
| Molecule type | protein |
| Topology | linear |
| Data_file_division | PLN |
| dblink | BioProject:PRJNA414658, BioSample:SAMN07821433 |
| db_source | QJKJ01005526.1 |
| Definition | Thiamine thiazole synthase 2, chloroplastic, partial [Mucuna pruriens] |
| Locus_tag | CR513_28258 |
EGGNOG-MAPPER Annotation
| COG_category | H |
| Description | Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance |
| KEGG_TC | - |
| KEGG_Module | - |
| KEGG_Reaction |
R10685
[VIEW IN KEGG] |
| KEGG_rclass |
RC00033
[VIEW IN KEGG] RC03253 [VIEW IN KEGG] RC03254 [VIEW IN KEGG] |
| BRITE |
ko00000
[VIEW IN KEGG] ko00001 [VIEW IN KEGG] |
| KEGG_ko |
ko:K03146
[VIEW IN KEGG] |
| EC | - |
| KEGG_Pathway |
ko00730
[VIEW IN KEGG] ko01100 [VIEW IN KEGG] map00730 [VIEW IN KEGG] map01100 [VIEW IN KEGG] |
| GOs | - |
Sequence
| CDS: ATGGCAGCCATGGCAACCACAACCCTCTCTTCAAACCCCAAACTCTCATTCTTCGATCACAAGCTCACCTCCTTCCACGGAAAGCCCGTTAGTTATTCCCGCGTGACACCCAGCAAATCCAGTTCTCAAAGCAAAATCTCCATGTCCCTAAACCCACCCCCATATGACTTGAGCTCCTTCAAGTTCCAACCCATCAAAGAGTCCATCGTCTCACGCGAGATGACGCGCCGCTACATGACCGACATGATAACCTACGCCGACACCGACGTGGTGGTGGTCGGTGCGGGCTCCGCAGGTCTGTCGTGCGCCTACGAGCTGAGCAAGAACCCGTCCATCCGCGTGGCCATCATCGAGCAGTCCGTGAGCCCGGGAGGTGGCGCGTGGCTGGGCGGGCAACTGTTCTCCGCCATGGTAGTGCGCAAGCCGGCGCACCTCTTCCTGGACGAGCTGGAAGTGGCGTACGACGAGCTAGAGGACTACGTGGTGATAAAGCACGCGGCGCTGTTCACGTCGACCATCATGAGTAAGCTTCTGGCGAGGCCGAACGTGAAGCTCTTCAACGCGGTGGCCGCGGAGGACTTGATCGTGAAGGAAGGGCGGGTGGCCGGGGTGGTCACCAACTGGGCGCTGGTTTCGATGAACCACGACACGCAGTCGTGCATGGACCCCAACGTCATGGAGGCTAAGGTTGTCGTGAGCTCTTGCGGGCACGATGGGCCTTTTGGCGCCACTGGGGTTAAGAGGTTGAAGACTATTGGCATGATCGATAGCGTTCCCGGAATGAAGGCCCTTGATATGAATACCGCCGAGGACGCTATTGTTAGGCTCACTAGGGAGGTTGTGCCTGGCATGATTGTCACTGGCATGGAGGTTGCAGAAATTGATGGCGCCCCAAGGATGGGTCCCACGTTTGGGGCGATGATGATATCAGGGCAGAAGGCGGCTCATTTGGCGTTGAAGGCGTTGGGGAGGAACAACGCAATTGATGGAACGTGTGGAATCGGAAGGGAAGAACCGGAGCTTGTTTTCGCTTCTGTGGACACTGAGGAAATTGTTGATGCTTGA |
| Protein: MAAMATTTLSSNPKLSFFDHKLTSFHGKPVSYSRVTPSKSSSQSKISMSLNPPPYDLSSFKFQPIKESIVSREMTRRYMTDMITYADTDVVVVGAGSAGLSCAYELSKNPSIRVAIIEQSVSPGGGAWLGGQLFSAMVVRKPAHLFLDELEVAYDELEDYVVIKHAALFTSTIMSKLLARPNVKLFNAVAAEDLIVKEGRVAGVVTNWALVSMNHDTQSCMDPNVMEAKVVVSSCGHDGPFGATGVKRLKTIGMIDSVPGMKALDMNTAEDAIVRLTREVVPGMIVTGMEVAEIDGAPRMGPTFGAMMISGQKAAHLALKALGRNNAIDGTCGIGREEPELVFASVDTEEIVDA |